Investment timing question: End of the Bush Tax Cuts

It is looking like the Bush Tax Cuts are going to expire. In light of this, would it be better to make a sizable cash donation to a not-for-profit organization in late 2010 and take the deduction this year or would it be better to wait until early January 2011 and take the deduction next year if the "tax bracket" is increased?

Assumption: my income would be the same for both years even though I hope this isn't the case.