First hand experience:
I just purchased a set of 265/70/16 Michelin LTX MS2 tires last last Friday. Here are my impressions so far. I did ALOT of research on tires, spent about a week comparing different tires, weights, load ratings, rolling resistance, P rated, sizes, ALL of that and here are my results. BTW I am coming from 265/75/16 Goodyear Duratracs.
First of all the reason I sold my Duratracs is simple. I do almost 97% ALL highway driving to school. My average day round trip especially if I have work after school is 222 + miles every other day! Yes you heard that correctly. While the Duratracs are simply amazing for they are designed for, they are simply not a highway tire and my MPG suffered greatly. So in choosing a highway tire, I wanted the absolute BEST highway tire money could buy. My truck is a long haul commuter, I'm not going to front and tell anyone otherwise. That is what it's for. So my goal was to find the best tire for the highway that would be lighter than my Duratracs, less rolling resistance, more conservative tread design for better MPG, excellent dry and wet traction, and a smooth quite ride. The Michelin LTX MS/2 is hands down the best tire for that. I don't think many will argue with that.
Now based on my research, I downgraded to a smaller size than my previous tires. If you look closely at the weight, a 265/70/16 Michelin LTX MS2 weighs in at 37 lbs. each tire. My 265/75/16 Duratracs weighed in at 45 lbs each tire. If saving weight and increasing MPG is your goal, than you want the lightest tire possible that will work on your application. You also want to look at a P-rated tire, versus a C,D, or E load range tire as most of those are going to be in 45+ lbs. Anyways just by going to the smaller Michelins based on weight savings alone I've reduced my rolling weight by 32 lbs which is nothing to sneeze at. The rolling resistance on these Michelins are night and day I can actually coast down the road with about 10-15% throttle on the pedal, whereas in my Duratracs I could only roll about 20 ft.
Today it rained and I wanted to really test the tires out in weather, hydroplaning conditions. I found and unbuilt shopping area with a huge parking lot and tried to get the Michelins to either break loose, fish tail, slide, anything. I'm telling you now these tires WOULD NOT BREAK LOOSE at all. The wet traction is EXCELLENT. I also live in the curvy hill country areas of central Texas and I was taking roads at high rates of speed and felt completely confident they would not break loose. The ride is EXCELLENT it feels very smooth and glides along the road. I can't speak on tread wear or life, but from what I'm reading in reviews these tires are known to go well past 75,000 miles. Other than looks, I'm very impressed with the tire and it's the best tire I've ever had on the truck in terms of shear road performance.
All Michelins have a 30-day no hassle return/exchange guarantee, a 70,000 mile tread warranty, and 3-years of FREE roadside assistance and FREE towing up to 150 miles.