Help please the following codes P0450, P0302, P0304, P0305

Yesterday I went to pass another vehicle on the interstate and when I pressed on the gas pedal to accelerate it failed to accelerate for several seconds then accelerated as it should. Immediately following the acceleration the truck began running rough and the check engine light started flashing. Since this occurred it's been running and idling very rough with the following codes, P0450, P0302, P0304, and P0305. I replaced the fuel cap about a week ago because of previous P0450 code (but ran fine) which cleared the code. About 500 miles ago I replaced spark plugs, plug wires, coil packs, pcv valve, and valve cover gaskets. My truck is a 2000 Tacoma PreRunner 3.4l with 210,000 miles on it. Any suggestions on where I should start?

 

Besides the P0450 those are all cylinder misfire codes. Since this happened have you looked at the plugs and coil packs yet?

 

Yes, they appear almost just as new as they did when I replaced them 500 miles ago.

 

The coil packs ground through the retaining bolt I believe. All grounds are good and tight? Battery and engine bay grounds clean and tight? Not sure what else would affect all three of those cylinders. Unless it's a blown head gasket/cracked head type of thing? Any other info from before? How is the coolant level? Smell sweet out the exhaust? Oil on dipstick is normal looking and not frothed up with coolant?

 

Replaced fuel pump yet ?.Nephews truck would have intermittent miss and hard starting when hot . After reading several threads on here replaced fuel pump (denso from rockauto ) since it has 194000 mi. Runs excellent now.His had miss fire code and lean down stream codes
Since you got 234000 mi if you haven't replaced fuel pump if you able to do it would be a good maintenance replacement at only about $90 with gasket pump and screen.

 

Everything appears to be snug. The first thing I checked was the oil after checking codes, all good.

 

This is a good possibility since mine has 210k. Since I've owned it, it seems like it takes a few seconds to start but starts fine. If that makes sense..

 

Is the MIL on solidly or is it blinking/flashing?
How about fuel filter? Last time that was changed?

 

That's the odd thing. The CIL only flashes when I accelerate and then goes off and remains off when I park it and let it idle but idles really rough. I will start with a new fuel filter and go from there, then fuel pump since it's an older truck with 210k miles and probably wouldn't hurt anyway. I plan on keeping it for a long time but I like my vehicles to be dependable, look nice, and run as close to new as possible so I'll replace whatever is needed.
I'm going to Raptor line it in "Jeep Tank Green" color in the spring and would like to put some nicer seats in it once I figure out how to do it properly.

 

All of the coil pack boots look good? Something with the ignition is being affected, whether that's not enough fuel or maybe coolant getting into the cylinder, etc affecting the ignition on those cylinders or something with the ignition components themselves not firing correctly. You got me curious

 

Might want to check compression before anything else to rule out mechanical problems .