Multiple misfire codes help!

i have the following codes
p0300 mutiple misfire
p0301-p0304 misfire on denoted cylinder.

my truck started running terribly one day and now it will not even run at all. about to change fuel filter. already changed MAF sensor. not sure where else to look. help would be much apreciated. also plugs are in decent shap and are firing as i checked all of them.
my truck has the 2.7l and is an '04

 

sorry to hear.
I propose you clean all grounds, and open each electric contact easy to reach,
clean with dremel round wire brush, add dielectric grease and put back together. I usually do
this when all is good, but today you are screwed.
need now age of plug wires. I am changing mine soon just to have new
wires and avoid issues like this. i do 600 miles a week in my 98 and change parts before
they die.

mikes 2 cents.

 

^^^^
http://www.obd-codes.com/p0300

go through this step-step. this is a serious problem.
don't drive your truck, you can do serious damage to the engine, and destroy your cat. very fast.
and use OEM parts....

 

Well I did also check both the cam and crank sensors and they have both check out. Was looking through various pids on my code reader and found that my second o2 sensor is getting zero volts and randomly peaking about a volt. Ill investigate further and let you guys know. I have also been following the step by step procedures via all data.

 

most of the time when ive seen the "p0300 random cyl misfire" code its been either a maf or coil, id check the coil since you said you already changed your maf

 

I have finally found the problem and its a bit angerinng but good to have my truck running again!

My front catalytic converter blew all to peice and got stuck in the second cat. hence my exhaust was plugged up. so now i have my truck running and also have to buy 2 new cats. thanks for all the help to contributors and suggestions!