Questions on my setup

Hey all...I have decided to change out the factory HU and speakers. I am going with the Alpine CDA-105 and the Alpine KTP-445 power pack. I am still up in the air about the two speaker models I am looking at. Both are Polk Audio..models MM6501 and DB6501. Anyone have this set up or something similar who can give me some feedback on either model of speakers?

Also, I am new to doing auto speaker installs. It's a 2010 Tacoma access cab. After looking at the factory speakers, it's look like they are component speakers with the crossover attached to the tweeter (can anyone verify?). Am I going to have to run new wires for either of the component systems I listed above? Is there no way to use the existing speaker wires to hook them up? Also, for the amp, is there a way to get it to sit behind the HU or in that area? I don't really want to put it in the glove box if I don't have to. Lastly, I know I will need speaker brackets for both the woofers and tweeters. Anyone know where the best deal for these would be? Anything else I am forgetting? Thanks for any info!!