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The Curious Case of Brooke Greenberg: 16-Year-Old Has the Body and Mind of a Toddler

Discussion in 'Off-Topic Discussion' started by Packman73, May 19, 2010.

  1. May 19, 2010 at 9:06 AM

    Packman73 [OP] ^^^^ 3%er ^^^^

    Aug 24, 2008
    First Name:
    The free state of Arizona
    2007 TRD Off Road
    Bilstein 5100's (front set @ .85"), OME 885's, chris4x4 anti-Taco-lean spacer on driver's side, Total Chaos UCAs, Rear Leaf Spring TSB, Toytec AALs, Black FJ TT Wheels, BFG 285/75R 16 AT Tires, TRD Exhaust, Viper Alarm, Fog Light Mod, De-badged, Blue LED Dome Light, EZ Clamped Tailgate, Wet Okoles, Satoshi Grill, 5% Tint, Engine Tick Fix, Black Rear Bumper, Black Center Valence, Exhaust Cut At Axle, Thanks for all the help chris4x4!
    Like most 16-year-olds, Brooke Greenberg enjoys shopping and listening to rock music.
    But unlike other girls her age who are learning to drive and going to the prom, Brooke still wears diapers, travels in a stroller and can’t walk or talk. Like a toddler, Brooke is 2-and-a-half feet tall and weighs only 16 pounds.
    “For the past 10, 11 years, she’s looked the same,” said Brooke’s father, Howard Greenberg. “The price is, she’s adorable. She stopped aging at the right age.”
    Doctors aren’t sure how or why, but Brooke, who lives in Baltimore, Md., developed a mutation of the gene that controls aging and development.
    Dr. Richard Walker, a biomedical researcher and editor-in-chief of Clinical Interventions in Aging, discovered Brooke’s mutated gene. He has been studying her case since 2006.
    “Brooke is a unique individual because she has a mutation in the developmental gene that prevents her from aging, and she’s in the developmental phase,” Walker said. “There’s no hope for her, but what she brings to science is information on how we may be able to delay aging.”

    Click here to see photos of Brooke
    Click here to watch Brooke and her family on 'FOX & Friends'
    Brooke, one of four children, is definitely a “Daddy’s girl.” Her father spares no expense for his daughter. Like her sisters, Brooke had a Bat Mitzvah — the Jewish rite of passage into adulthood — when she turned 13. And he buys her the best strollers and baby swings.
    “That’s what she really loves,” said Caitlin Greenberg, 19, pointing to the swing, as Brooke propelled herself back and forth, a smile forming on her small face.
    Caitlin, a sophomore at Towson University, and her other sisters, Emily, 22, and Carly, 13, are of normal size and development. They still interact with their “little” sister as if “she’s just one of the gals,” Caitlin said.
    But it’s a difficult life for the Greenbergs. The state of Maryland has provided two nurses to help care for Brooke 16 hours a day, because she was getting sick often and needed a feeding tube inserted in her stomach.
    “From the ages of 1 to 5, she spent 65 percent of her life in the hospital,” her mom, Melanie, said. “It takes her 10 hours a day just to eat. She’s medically fragile.”
    According to Walker, development and aging are at opposite poles of the life continuum, but they are controlled by the same genes. In young childhood, these genes initiate structure and function and coordinate change (single cells eventually become full-functioning adults).
    “Once we’re adults, we don’t want to change,” Walker said. “We all want our bodies to be about 21. But those genes don’t turn off at that time. It causes the bodies’ stability to erode, and that’s what aging is. The punchline: if you can get those genes and turn them off, then you wouldn’t have aging.”
    Essentially, Brooke’s aging and development genes have been turned off.
    Her bones are that of a 10-year-old, her teeth are 6-years-old, her brain is less than a year old, Walker said.
    Yet, her hair and nails, protein synthesis, grow normally.
    “We’re still searching for the mutation,” Walker said. “Once we find it, we are going to try to manipulate it in experimental animals to see if we can extend their lifespan.”
    In the meantime, the Greenberg family takes each day with Brooke as it comes. They don’t dwell on the negative; instead, they consider Brooke’s life a gift.
    “Maybe she holds the keys to medical history,” Caitlin said.
  2. May 19, 2010 at 9:55 AM

    Loudpedal Mind = Blown

    Oct 2, 2009
    First Name:
    Not really New, not really Mexico
    02 SR5-Hole 4x4
    Andres Devil Horns, Goodyear Duratracs, Accidental Tailgate Delete (x2), Billy 5100s, OME 881 coils, Wheeler's 5-leafs, BAMF Sliders with kickouts, Box Rocket Fab Bedrack.
    Moving story. Lots more questions than answers. Stories like this remind me of how many things have to go right to have a "normal" kid. I am so thankful to God that both of mine are very healthy. I think I need to go home and hug my kids now.
  3. May 19, 2010 at 10:03 AM

    tacomakid89 Awesome Member

    Dec 22, 2009
    First Name:
    SoCal, CA
    2010 Black, 4x4, TRD Sport Tacoma
    Hard Wired GPS, Scan Guage II, URD Short Throw Shifter, AFE Pro Dry S Air Filter, LED Mag Lite on seat side,Tailgate Theft Prevention Mod, Removed Front License Plate, Tint Cover Over Rear License Plate, Removed Secondary Air Filter, 13" Shorty Antenna, 5% Tint Rear, 20% Tint Front, Bed Extender, TRD Cat Back Exhaust, Fog Light On Anytime Mod, Dual Halo Projection Headlights, Disabled Seatbelt Chime
    Thats too bad.
  4. May 19, 2010 at 10:11 AM

    BakoTruck Well-Known Member

    May 1, 2009
    First Name:
    Herbie Hancock
    Bakersfield, CA
    05 PreRunner TRD
    Mostly stock for now, I have added a cb radio, various cheap mods and I plan on adding aftermarket wheels and other items in the future.
    That's sad.

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